Description

1-(2-Cyano-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex molecules, enabling the exploration of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Peptidomimetic Research: Used to construct modified peptide backbones to enhance stability, bioavailability, and receptor selectivity in drug design.
• Chemical Biology Probe Synthesis: Employed in creating specialized molecular tools for studying enzyme function and biological pathways.
• Ligand Library Development: A valuable component for generating diverse compound libraries used in high-throughput screening for drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Used in university and institutional laboratories for fundamental studies in medicinal chemistry and organic synthesis methodologies.

Basic Information

Product Name	1-(2-Cyano-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride
CAS No.	1353943-58-4
Molecular Formula	C13H16N4O2 • HCl
Molecular Weight	296.75 g/mol
Synonyms	1-[(2-Cyanophenyl)methyl]piperazine-2-carboxylic acid hydrochloride; (S)-1-(2-Cyanobenzyl)piperazine-2-carboxylic acid hydrochloride; 2-Cyanobenzyl-piperazine-2-carboxylic acid HCl; 1-(2-CN-Bn)-Piperazine-2-COOH • HCl; Piperazine-2-carboxylic acid, 1-[(2-cyanophenyl)methyl]-, hydrochloride (1:1); 1353943-58-4; 1-(2-Cyano-benzyl)-piperazine-2-carboxylic acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our 1-(2-Cyano-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.