Description

2,4-Dibromo-3-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its precise halogen substitution pattern offers unique reactivity for selective cross-coupling and nucleophilic substitution reactions, enabling the construction of complex heterocyclic architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating specialized electronic and optoelectronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen handles for structural diversification.
• Ligand and Catalyst Development: Serves as a scaffold for creating sophisticated nitrogen-containing ligands for transition metal catalysis.
• Material Science Building Block: Integral in the synthesis of organic semiconductors, liquid crystals, and other functional materials requiring specific halogenated pyridine cores.
• Chemical Research & Development: A versatile reagent for method development in cross-coupling (e.g., Suzuki, Stille, Negishi) and halogen-metal exchange reactions.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, multi-halogenated intermediates.

Basic Information

Product Name	2,4-Dibromo-3-Iodopyridine
CAS No.	1353056-48-0
Molecular Formula	C5H2Br2IN
Molecular Weight	402.79 g/mol
Synonyms	3-Iodo-2,4-dibromopyridine; Pyridine, 2,4-dibromo-3-iodo-; 2,4-Dibromo-3-iodopyridine; 1353056-48-0; 3-Iodo-2,4-dibromopyridine
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-3-Iodopyridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.