Description

4-Amino-5-Iodo-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring amino, iodo, and nitro substituents on a pyridine core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a building block for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex aryl/alkynyl groups.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes and tags for studying biological systems.
• Dye and Pigment Research: Acts as an intermediate in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	4-Amino-5-Iodo-3-Nitropyridine
CAS No.	1352905-69-1
Molecular Formula	C5H4IN3O2
Molecular Weight	264.99 g/mol
Synonyms	5-Iodo-3-nitro-4-pyridinamine; 3-Nitro-5-iodopyridin-4-amine; 4-Pyridinamine, 5-iodo-3-nitro-; 4-Amino-3-nitro-5-iodopyridine; 5-Iodo-4-amino-3-nitropyridine; Building Block 1352905-69-1
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Iodo-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.