Description

Imidazo[1,5-A]Pyrazine, 1-Bromo-8-Chloro- is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities for structure-activity relationship (SAR) studies or to enable further cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the imidazopyrazine core imparts specific biological activity.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for versatile metal-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig amination.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, tags, or linkers used in bioconjugation and target identification studies.
• Academic & Contract Research: Essential for methodological development and exploration of new synthetic pathways in university and CRO laboratory settings.

Basic Information

Item	Detail
Product Name	Imidazo[1,5-A]Pyrazine, 1-Bromo-8-Chloro-
CAS No.	1352897-61-0
Molecular Formula	C6H3BrClN3
Molecular Weight	232.47 g/mol
Synonyms	1-Bromo-8-chloroimidazo[1,5-a]pyrazine; 8-Chloro-1-bromoimidazo[1,5-a]pyrazine; Imidazo[1,5-a]pyrazine, 1-bromo-8-chloro-; 1-Bromo-8-chloro-imidazo[1,5-a]pyrazine; 1352897-61-0; Bromochloroimidazopyrazine; Halogenated imidazopyrazine derivative
EINECS	Contact for details

Quality Control

Our Imidazo[1,5-A]Pyrazine, 1-Bromo-8-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (including HPLC, NMR, and MS) are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.