Description

5-Chloro-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials due to its unique pyrazolopyridine scaffold. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and tool compounds in biochemical and pharmacological studies.
• Material Science: A potential building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and scale-up projects.

Basic Information

Product Name	5-Chloro-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1352397-08-0
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	5-Chloro-3-methyl-1H-pyrazolo[3,4-b]pyridine; 3-Methyl-5-chloro-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 5-chloro-3-methyl-; 5-Chloro-3-methylpyrazolo[3,4-b]pyridine; 5-Chloro-3-methyl-1H-pyrazolo[3,4-b]pyridine; 1352397-08-0 (CAS); 5-Chloro-3-methyl-1H-pyrazolo[3,4-b]pyridin
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.