Description

1-(3-(Methylsulfonyl)Phenyl)Piperazine Hydrochloride is a high-purity, synthetically derived organic compound primarily used as a key pharmaceutical intermediate in modern drug discovery and development. Its value lies in its role as a versatile building block for creating novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric therapeutic areas. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of new chemical entities (NCEs) and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for CNS-targeting therapies.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex API manufacturing.
• Biochemical Research: Employed as a tool compound in pharmacological assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis projects and scale-up production under cGMP conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	1-(3-(Methylsulfonyl)Phenyl)Piperazine Hydrochloride
CAS No.	1352305-13-5
Molecular Formula	C11H16ClN2O2S
Molecular Weight	275.77 g/mol
Synonyms	1-(3-Methanesulfonylphenyl)piperazine hydrochloride; 3-(1-Piperazinyl)benzenesulfonamide, N-methyl-, hydrochloride; 1-(3-Methylsulfonylphenyl)piperazine HCl; 1-(3-(Methylsulfonyl)phenyl)piperazine HCl; Piperazine, 1-[3-(methylsulfonyl)phenyl]-, hydrochloride; 1352305-13-5; 1-(3-Methanesulphonylphenyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-(Methylsulfonyl)Phenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.