Description

Pyrazolo[1,5-A]Pyridin-3-Yl-Methylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound matters as a critical precursor in the development of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting central nervous system and oncological pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds. Its structural motif is highly valued for creating molecules with specific biological activity and optimized pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its heterocyclic scaffold.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological systems.
• Material Science: Potential precursor for the synthesis of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in academic and CRO settings.
• Library Synthesis: Used in combinatorial and parallel synthesis to create diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyridin-3-Yl-Methylamine Hydrochloride
CAS No.	1351659-25-0
Molecular Formula	C9H11ClN4
Molecular Weight	210.66 g/mol
Synonyms	3-(Aminomethyl)pyrazolo[1,5-a]pyridine hydrochloride; 1H-Pyrazolo[1,5-a]pyridin-3-ylmethanamine hydrochloride; Pyrazolo[1,5-a]pyridin-3-ylmethylamine HCl; (Pyrazolo[1,5-a]pyridin-3-yl)methanamine hydrochloride; 1351659-25-0; Aminomethylpyrazolopyridine hydrochloride; 3-Aminomethylpyrazolo[1,5-a]pyridine HCl
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyridin-3-Yl-Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.