Description

4-(5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Piperidine Hydrochloride is a high-purity, non-racemic chiral building block and pharmaceutical intermediate. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and advanced material scientists seeking to incorporate its unique heterocyclic piperidine-oxadiazole scaffold.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Ligand and Catalyst Development: The piperidine-oxadiazole structure can be utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	4-(5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Piperidine Hydrochloride
CAS No.	1351502-90-3
Molecular Formula	C11H20ClN3O
Molecular Weight	245.75 g/mol
Synonyms	4-(5-tert-Butyl-1,2,4-oxadiazol-3-yl)piperidine HCl; 4-(5-tert-Butyl-[1,2,4]oxadiazol-3-yl)-piperidine hydrochloride; 3-Piperidin-4-yl-5-tert-butyl-1,2,4-oxadiazole hydrochloride; 4-(5-(tert-Butyl)-1,2,4-oxadiazol-3-yl)piperidine hydrochloride; 1351502-90-3; tert-Butyl Oxadiazole Piperidine HCl
EINECS	Contact for details

Quality Control

Our 4-(5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.