Description

Bis-Propargyl-Peg10 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring terminal propargyl groups. This compound is engineered for precision conjugation and bioconjugation applications, offering a hydrophilic spacer with defined length and reactivity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, functional linkers for click chemistry, polymer synthesis, and surface modification.

Application

• As a versatile linker for click chemistry (CuAAC) reactions in bioconjugation and drug delivery system development.
• Functionalization of nanoparticles, surfaces, and polymers to introduce alkyne handles for subsequent modification.
• Intermediate in the synthesis of PEGylated therapeutics and diagnostic agents.
• Preparation of hydrogels and biomaterials with tailored cross-linking density and biocompatibility.
• Conjugation of peptides, oligonucleotides, or small molecules to create novel chemical entities for screening.
• As a building block for synthesizing complex dendrimers and star-shaped polymers.
• Surface modification of biosensors and diagnostic devices to enhance specificity and reduce non-specific binding.

Basic Information

Product Name	Bis-Propargyl-Peg10
CAS No.	1351373-48-2
Molecular Formula	C28H50O11
Molecular Weight	562.7 g/mol
Synonyms	α,ω-Bis(2-propynyl)-PEG10; Propargyl-PEG10-Propargyl; 1,1'-[1,11-Dioxo-3,6,9-trioxa-2,10-diazadodecane-1,11-diyl]bis(2-propyn-1-ol) (related structure); Bis-propargyl PEG 500; PEG10 dialkyne; Alkyne-PEG10-Alkyne; Heterobifunctional PEG Alkyne; 2,5,8,11,14,17,20,23,26,29-Decaoxahentriacont-30-yne-1,31-diyl bis(2-propyn-1-yl) ether
EINECS	Contact for details

Quality Control

Our Bis-Propargyl-Peg10 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Average Molecular Weight (GPC)	550 - 580 g/mol
Functional Group Assay (NMR)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.