Description

6-Bromo-5-Chloropyrazin-2-Amine is a high-purity halogenated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated amine functionality into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized heterocyclic compounds used in organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed as a molecular probe or a tagging reagent due to its reactive amine and halogen groups.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise halogenation patterns on nitrogen-containing heterocycles.

Basic Information

Product Name	6-Bromo-5-Chloropyrazin-2-Amine
CAS No.	1350885-68-5
Molecular Formula	C4H3BrClN3
Molecular Weight	208.44 g/mol
Synonyms	5-Chloro-6-bromopyrazin-2-amine; 2-Amino-5-chloro-6-bromopyrazine; 6-Bromo-5-chloro-2-pyrazinamine; 5-Chloro-6-bromo-2-aminopyrazine; 2-Pyrazinamine, 6-bromo-5-chloro-; 1350885-68-5; 6-Bromo-5-chloropyrazine-2-amine
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloropyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.