Description

7-Iodo-1H-Pyrazolo[4,3-B]Pyridin-3-Ylamine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted kinase inhibitors. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Used as a tool compound or a labeled probe in biochemical assays and target validation studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for specialized applications.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	7-Iodo-1H-Pyrazolo[4,3-B]Pyridin-3-Ylamine
CAS No.	1350648-21-3
Molecular Formula	C6H5IN4
Molecular Weight	260.03 g/mol
Synonyms	3-Amino-7-iodo-1H-pyrazolo[4,3-b]pyridine; 7-Iodo-1H-pyrazolo[4,3-b]pyridin-3-amine; 1H-Pyrazolo[4,3-b]pyridin-3-amine, 7-iodo-; 1350648-21-3; 7-Iodo-3-amino-1H-pyrazolo[4,3-b]pyridine; 7-Iodo-1H-pyrazolo[4,3-b]pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 7-Iodo-1H-Pyrazolo[4,3-B]Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP standards ensures reliable material for your most sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.