Description

1-tert-Butyl 4-Methyl 4-(Cyanomethyl)Piperidine-1,4-Dicarboxylate is a high-purity, protected piperidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, enabling efficient multi-step synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized piperidine core.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and advanced materials requiring specific chiral or protected intermediates.
• Process Chemistry: Serves as a standardized intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	1-tert-Butyl 4-Methyl 4-(Cyanomethyl)Piperidine-1,4-Dicarboxylate
CAS No.	1350475-42-1
Molecular Formula	C14H22N2O4
Molecular Weight	282.34 g/mol
Synonyms	4-(Cyanomethyl)-1-(tert-butoxycarbonyl)-4-(methoxycarbonyl)piperidine; 1-Boc-4-(methoxycarbonyl)-4-(cyanomethyl)piperidine; tert-Butyl 4-(cyanomethyl)-4-(methoxycarbonyl)piperidine-1-carboxylate; 4-Cyanomethyl-4-methoxycarbonyl-piperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-(cyanomethyl)-4-piperidinecarboxylic acid methyl ester; Methyl 1-(tert-butoxycarbonyl)-4-(cyanomethyl)-4-piperidinecarboxylate; 1350475-42-1; 4-(Cyanomethyl)-N-Boc-4-piperidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl 4-(Cyanomethyl)Piperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.