Description

Racemic-(3S,3Ar,7Ar)-tert-Butyl 3-(Aminomethyl)Hexahydrofuro[3,4-C]Pyridine-5(3H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex, fused bicyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of complex small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, constrained molecular scaffold.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for target APIs.
• Asymmetric Synthesis: Utilized as a building block to introduce stereochemical complexity in the synthesis of enantiomerically pure compounds.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Racemic-(3S,3Ar,7Ar)-tert-Butyl 3-(Aminomethyl)Hexahydrofuro[3,4-C]Pyridine-5(3H)-Carboxylate
CAS No.	1350475-38-5
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	tert-Butyl 3-(aminomethyl)hexahydrofuro[3,4-c]pyridine-5(3H)-carboxylate; (3S,3aR,7aR)-tert-Butyl 3-(aminomethyl)hexahydro-1H-furo[3,4-c]pyridine-5-carboxylate; 1H-Furo[3,4-c]pyridine-5-carboxylic acid, 3-(aminomethyl)hexahydro-, 1,1-dimethylethyl ester, (3S,3aR,7aR)-; 1350475-38-5; tert-Butyl (3S,3aR,7aR)-3-(aminomethyl)hexahydrofuro[3,4-c]pyridine-5-carboxylate; Furo[3,4-c]pyridine intermediate; Bicyclic amino ester intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and chiral purity assessment, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.