Description

6-(Aminomethyl)Pyridine-3-Carbonitrile Dihydrochloride is a versatile and high-purity chemical building block, primarily valued for its bifunctional pyridine and amine moieties. This compound is critical for facilitating complex molecular synthesis, enabling the development of novel active ingredients in pharmaceutical and agrochemical research. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce both aminomethyl and nitrile functional groups into target molecules.
• Bioconjugation Chemistry: The amine group facilitates conjugation reactions, useful in probe and linker development for biochemical applications.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.

Basic Information

Product Name	6-(Aminomethyl)Pyridine-3-Carbonitrile Dihydrochloride
CAS No.	1350362-43-4
Molecular Formula	C7H8N3·2HCl
Molecular Weight	207.08 g/mol (Free base: 133.16 g/mol)
Synonyms	3-Cyano-6-(aminomethyl)pyridine dihydrochloride; 6-(Aminomethyl)nicotinonitrile dihydrochloride; 2-(Aminomethyl)-5-cyanopyridine dihydrochloride; (6-Aminomethyl-pyridin-3-yl)-acetonitrile dihydrochloride; 5-Cyano-2-(aminomethyl)pyridine dihydrochloride; Pyridine-3-carbonitrile, 6-(aminomethyl)-, dihydrochloride; 6-(Aminomethyl)-3-pyridinecarbonitrile dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-(Aminomethyl)Pyridine-3-Carbonitrile Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	95.0% - 105.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.