Description

1-(Pyridin-2-Yl)Cyclopropanecarboxylic Acid Hydrochloride is a high-purity organic salt building block of significant interest in advanced chemical synthesis. This compound is valued for its rigid cyclopropane ring fused with a pyridine moiety, which is crucial for modulating the physicochemical properties and biological activity of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with improved metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the cyclopropane scaffold can enhance potency and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Chemical Biology Research: Employed as a probe or building block in the study of enzyme inhibition and receptor-ligand interactions.
• Material Science Precursor: Potential use in the synthesis of functionalized organic materials and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	1-(Pyridin-2-Yl)Cyclopropanecarboxylic Acid Hydrochloride
CAS No.	1349716-23-9
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	1-(2-Pyridinyl)cyclopropanecarboxylic acid hydrochloride; 1-(Pyridin-2-yl)cyclopropane-1-carboxylic acid HCl; 2-(1-Carboxycyclopropyl)pyridine hydrochloride; Cyclopropanecarboxylic acid, 1-(2-pyridinyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Every batch of 1-(Pyridin-2-Yl)Cyclopropanecarboxylic Acid Hydrochloride is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical R&D and scale-up activities. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.