Description

(R)-tert-Butyl 3-[(Pyridin-2-Ylmethyl)Amino]Piperidine-1-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with targeted biological activity. This advanced intermediate is essential for research and development chemists in the pharmaceutical and biotechnology industries, particularly for creating novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• API Synthesis: Used as a building block in the multi-step synthesis of complex, stereochemically pure Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in fine chemicals.

Basic Information

Product Name	(R)-tert-Butyl 3-[(Pyridin-2-Ylmethyl)Amino]Piperidine-1-Carboxylate
CAS No.	1349702-19-7
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	1-Boc-3-[(2-pyridylmethyl)amino]-(R)-piperidine; (R)-1-(tert-Butoxycarbonyl)-3-[(pyridin-2-ylmethyl)amino]piperidine; (R)-N-[(1-Boc-piperidin-3-yl)]-2-picolylamine; (R)-tert-Butyl 3-(2-picolylamino)piperidine-1-carboxylate; (R)-3-[(Pyridin-2-ylmethyl)amino]piperidine-1-carboxylic acid tert-butyl ester; (R)-1-Boc-3-(2-picolylamino)piperidine; (R)-Boc-3-(2-picolylamino)piperidine; (R)-tert-Butyl 3-[(2-pyridinylmethyl)amino]-1-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-[(Pyridin-2-Ylmethyl)Amino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.