Description

(S)-2-Methoxy-n-(Piperidin-3-Yl)Acetamide Hydrochloride is a high-purity chiral intermediate and building block of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly those with defined stereochemistry required for biological activity. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), especially within therapeutic areas targeting the central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of potential APIs where the (S)-piperidin-3-yl moiety is a critical pharmacophore.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing focused libraries of compounds for structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Asymmetric Synthesis: Utilized in reactions requiring enantiomerically pure amines to induce or maintain chirality in final products.
• Bioconjugation & Probe Development: Can be functionalized for use in creating biochemical probes or antibody-drug conjugates (ADCs).

Basic Information

Product Name	(S)-2-Methoxy-n-(Piperidin-3-Yl)Acetamide Hydrochloride
CAS No.	1349700-02-2
Molecular Formula	C9H19ClN2O2
Molecular Weight	222.71 g/mol
Synonyms	(S)-2-Methoxy-N-(piperidin-3-yl)acetamide hydrochloride; (3S)-2-Methoxy-N-(3-piperidyl)acetamide hydrochloride; (S)-N-(Piperidin-3-yl)-2-methoxyacetamide HCl; 2-Methoxy-N-[(3S)-piperidin-3-yl]acetamide hydrochloride; (S)-3-(2-Methoxyacetamido)piperidine hydrochloride; UNII-9F6F2K0Q8F; 9F6F2K0Q8F; (S)-2-Methoxyacetamide piperidine-3-yl hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Methoxy-n-(Piperidin-3-Yl)Acetamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided for every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.