Description

(S)-n-(Piperidin-3-Yl)Morpholine-4-Carboxamide Hydrochloride is a high-purity chiral building block and intermediate of significant value in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of targeted pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Utilized in the construction of complex, enantiomerically pure molecules due to its defined stereochemistry.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds.

Basic Information

Product Name	(S)-n-(Piperidin-3-Yl)Morpholine-4-Carboxamide Hydrochloride
CAS No.	1349699-87-1
Molecular Formula	C10H20N3O2 • HCl
Molecular Weight	247.75 g/mol (Free base: 211.29 g/mol)
Synonyms	(S)-N-(Piperidin-3-yl)morpholine-4-carboxamide hydrochloride; (S)-3-(4-Morpholinecarboxamido)piperidine hydrochloride; (S)-Morpholine-4-carboxylic acid (3-piperidinyl)-amide hydrochloride; (S)-N-(3-Piperidinyl)morpholine-4-carboxamide HCl; (S)-3-(Morpholine-4-carboxamido)piperidine hydrochloride; (S)-Piperidin-3-yl-morpholine-4-carboxamide HCl
EINECS	Contact for details

Quality Control

Our (S)-n-(Piperidin-3-Yl)Morpholine-4-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.