Description

(R)-3-Methyl-1-(Piperidin-3-Yl)Urea Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and functionalized piperidine core, which are critical for the development of targeted bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in neurological and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Asymmetric Synthesis: Serves as a valuable starting material or reagent in stereoselective synthesis due to its (R)-configured stereocenter.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Process Chemistry Development: Used in scaling up synthetic routes for potential drug candidates during preclinical and clinical development phases.

Basic Information

Product Name	(R)-3-Methyl-1-(Piperidin-3-Yl)Urea Hydrochloride
CAS No.	1349699-82-6
Molecular Formula	C8H18ClN3O
Molecular Weight	207.70 g/mol
Synonyms	(R)-3-Methyl-1-(3-piperidyl)urea hydrochloride; (R)-1-(Piperidin-3-yl)-3-methylurea hydrochloride; Urea, N-[(3R)-3-piperidinyl]-N-methyl-, monohydrochloride; (R)-N-Methyl-N'-(piperidin-3-yl)urea hydrochloride; (3R)-3-Methyl-1-(piperidin-3-yl)urea hydrochloride; (R)-3-Methyl-1-(3-piperidinyl)urea HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Methyl-1-(Piperidin-3-Yl)Urea Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.