Description

6H-Pyrido[1,2-B]Pyridazin-6-One, 2-(2,4-Difluorophenoxy)-5-[2-Methoxy-5-(5-Methyl-1,3,4-Oxadiazol-2-Yl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate with the CAS number 1349264-72-7. This heterocyclic compound is valued for its complex molecular architecture, which is critical for imparting specific biological activity in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Oncology Research: Used in the R&D of small molecule inhibitors targeting specific kinase pathways involved in cancer cell proliferation.
• Antiviral Drug Development: Serves as a core scaffold in the design of compounds for antiviral applications.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and cellular signaling pathways.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale manufacturing of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and development services.

Basic Information

Item	Details
Product Name	6H-Pyrido[1,2-B]Pyridazin-6-One, 2-(2,4-Difluorophenoxy)-5-[2-Methoxy-5-(5-Methyl-1,3,4-Oxadiazol-2-Yl)Phenyl]-
CAS No.	1349264-72-7
Molecular Formula	C23H16F2N4O4
Molecular Weight	450.40 g/mol
Synonyms	2-(2,4-Difluorophenoxy)-5-[2-methoxy-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]pyrido[1,2-b]pyridazin-6-one; 1349264-72-7; UNII-9K7I8V9V1P; 9K7I8V9V1P; Pyrido[1,2-b]pyridazin-6-one, 2-(2,4-difluorophenoxy)-5-[2-methoxy-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]-; 2-(2,4-Difluorophenoxy)-5-(2-methoxy-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl)-6H-pyrido[1,2-b]pyridazin-6-one
EINECS	Contact for details

Quality Control

Our 6H-Pyrido[1,2-B]Pyridazin-6-One intermediate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.