Description

tert-Butyl 4-(3-Chloropyrazin-2-yl)piperidine-1-carboxylate is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyrazine moiety for biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or advanced functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	tert-Butyl 4-(3-Chloropyrazin-2-yl)piperidine-1-carboxylate
CAS No.	1349184-43-5
Molecular Formula	C14H18ClN3O2
Molecular Weight	295.77 g/mol
Synonyms	1-Boc-4-(3-chloropyrazin-2-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(3-chloropyrazin-2-yl)piperidine; 4-(3-Chloro-2-pyrazinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(3-chloro-2-pyrazinyl)-1-piperidinecarboxylate; 1-Boc-4-(3-chloro-2-pyrazinyl)piperidine; 1349184-43-5; BOC-4-(3-Chloropyrazin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Chloropyrazin-2-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.