Description

3,4,6,7,8,9-Hexahydropyrido[3,4-B]Indolizin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the indolizine class of heterocyclic compounds. Its complex fused-ring structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used for route scouting, optimization, and scale-up studies for the production of target APIs.
• Fine Chemical Synthesis: Employed in the preparation of specialty chemicals, catalysts, and ligands requiring the indolizine moiety.
• Academic Research: A valuable compound for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.

Basic Information

Product Name	3,4,6,7,8,9-Hexahydropyrido[3,4-B]Indolizin-1(2H)-One
CAS No.	1346672-96-5
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	Hexahydropyrido[3,4-b]indolizin-1(2H)-one; 1,2,3,4,6,7,8,9-Octahydropyrido[3,4-b]indolizin-1-one; Pyrido[3,4-b]indolizine-1(2H)-one, 3,4,6,7,8,9-hexahydro-; 1346672-96-5; 3,4,6,7,8,9-Hexahydro-2H-pyrido[3,4-b]indolizin-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Quality is managed in line with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.