Description

5-Amino-2-Methylnicotinonitrile (CAS NO 1346542-14-0) is a high-purity, versatile nitrile-substituted aminopyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Development: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Amino-2-Methylnicotinonitrile
CAS No.	1346542-14-0
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	5-Amino-2-methylpyridine-3-carbonitrile; 3-Cyano-2-methyl-5-aminopyridine; 2-Methyl-5-aminonicotinonitrile; 5-Amino-2-methyl-3-cyanopyridine; 2-Methyl-5-aminopyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 5-amino-2-methyl-; 5-Amino-2-methyl-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Methylnicotinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from atmospheric moisture and light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.