Description

5-Bromo-2-Iodo-Nicotinonitrile is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Material Science: Building block for creating specialized ligands, organic semiconductors, and liquid crystal compounds.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl systems.
• Chemical Synthesis: Intermediate for further functionalization to create libraries of compounds for high-throughput screening.

Basic Information

Product Name	5-Bromo-2-Iodo-Nicotinonitrile
CAS No.	1346540-97-3
Molecular Formula	C6H2BrIN2
Molecular Weight	308.90 g/mol
Synonyms	5-Bromo-2-iodopyridine-3-carbonitrile; 3-Cyano-5-bromo-2-iodopyridine; 2-Iodo-5-bromonicotinonitrile; 5-Bromo-2-iodo-3-pyridinecarbonitrile; Nicotinonitrile, 5-bromo-2-iodo-; 5-Bromo-2-iodo-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.