Description

5-Bromo-2-(Dimethylamino)Nicotinonitrile is a high-value, multi-functional chemical intermediate featuring a brominated pyridine core. This compound matters for its role as a versatile building block in modern synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern allows for precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and liquid crystals.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex amine and nitrile functionalities.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	5-Bromo-2-(Dimethylamino)Nicotinonitrile
CAS No.	1346537-10-7
Molecular Formula	C8H8BrN3
Molecular Weight	226.08 g/mol
Synonyms	5-Bromo-2-(dimethylamino)nicotinonitrile; 2-(Dimethylamino)-5-bromonicotinonitrile; 5-Bromo-2-(N,N-dimethylamino)nicotinonitrile; 3-Cyano-5-bromo-2-(dimethylamino)pyridine; Nicotinonitrile, 5-bromo-2-(dimethylamino)-; 1346537-10-7
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Dimethylamino)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.