Description

3-Cyclopropyl-2-Methylpyridine CAS NO 1346533-28-5 is a high-purity, functionalized pyridine derivative characterized by its unique cyclopropyl and methyl substituents. This compound serves as a versatile and valuable advanced pharmaceutical intermediate and key building block in modern organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the construction of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for developing new generation pesticides, herbicides, and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: The pyridine core and cyclopropyl group make it suitable for creating novel ligands for metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of specialty chemicals, functional polymers, and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tool compounds for biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-Cyclopropyl-2-Methylpyridine
CAS No.	1346533-28-5
Molecular Formula	C9H11N
Molecular Weight	133.19 g/mol
Synonyms	2-Methyl-3-cyclopropylpyridine; 3-Cyclopropyl-2-picoline; Pyridine, 3-cyclopropyl-2-methyl-; 2-Methyl-3-(cyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Cyclopropyl-2-Methylpyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.