Description

5-Ethynyl-2-Phenylpyridine is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its molecular structure, featuring both a phenylpyridine core and an ethynyl group, makes it a critical precursor in modern synthetic chemistry, particularly for cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new active ingredients for crop protection and pest control formulations.
• Material Science: Serves as a monomer or linker in the creation of advanced polymers, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Synthesis: A versatile reagent for Sonogashira and other palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and coordination chemistry.
• Academic & R&D: Fundamental research compound in organic chemistry and medicinal chemistry laboratories for method development and discovery.

Basic Information

Product Name	5-Ethynyl-2-Phenylpyridine
CAS No.	1346462-88-1
Molecular Formula	C13H9N
Molecular Weight	179.22 g/mol
Synonyms	2-Phenyl-5-ethynylpyridine; 5-Ethynyl-2-phenylpyridine; 2-(Phenyl)-5-ethynylpyridine; 5-Ethynyl-2-phenyl-pyridine; Pyridine, 5-ethynyl-2-phenyl-; (5-Ethynyl-2-pyridinyl)benzene
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Phenylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.