Description

tert-Butyl (5-(Trifluoromethyl)-1H-Pyrrolo-[2,3-B]Pyridin-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyrrolopyridine core and trifluoromethyl group. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Serves as a precursor for labeled probes or active pharmaceutical ingredients (APIs) in preclinical studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences sector.

Basic Information

Product Name	tert-Butyl (5-(Trifluoromethyl)-1H-Pyrrolo-[2,3-B]Pyridin-4-Yl)Carbamate
CAS No.	1346447-44-6
Molecular Formula	C13H14F3N3O2
Molecular Weight	301.27 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester; Boc-4-amino-5-trifluoromethyl-7-azaindole; tert-Butyl N-[5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]carbamate; 4-N-Boc-amino-5-trifluoromethyl-7-azaindole
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-(Trifluoromethyl)-1H-Pyrrolo-[2,3-B]Pyridin-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.