Description

tert-Butyl 1H-Pyrrolo[2,3-B]Pyridin-6-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyridine class of heterocyclic compounds. This compound is of significant commercial importance as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development and commercial production of novel kinase inhibitor drugs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities targeting various disease pathways.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale synthesis of candidate drugs before full-scale GMP manufacturing.
• Biochemical Research: Acts as a tool compound or a ligand core in biochemical assays to study enzyme function and cellular signaling.
• Custom Synthesis: A starting material for the custom synthesis of more complex, functionalized pyrrolopyridine derivatives for specialized applications.

Basic Information

Item	Detail
Product Name	tert-Butyl 1H-Pyrrolo[2,3-B]Pyridin-6-Ylcarbamate
CAS No.	1346447-43-5
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	6-(((tert-Butoxy)carbonyl)amino)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-6-amine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl (1H-pyrrolo[2,3-b]pyridin-6-yl)carbamate; Boc-6-amino-1H-pyrrolo[2,3-b]pyridine; 6-N-Boc-amino-7-azaindole; 6-Boc-amino-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1H-Pyrrolo[2,3-B]Pyridin-6-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.