Description

tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Carbamate is a sophisticated heterocyclic building block and protected amine derivative of significant value in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of complex, biologically active molecules, offering chemists a versatile handle for further functionalization. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fused dioxino-pyridine scaffold.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems and introducing the tert-butyloxycarbonyl (Boc) protecting group.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and tool compounds for studying biological pathways and target engagement.
• Material Science Research: Potential intermediate for the synthesis of specialty chemicals and functional organic materials.

Basic Information

Product Name	tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Carbamate
CAS No.	1346447-37-7
Molecular Formula	C₁₂H₁₆N₂O₄
Molecular Weight	252.27 g/mol
Synonyms	8-Boc-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; tert-Butyl 2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-8-ylcarbamate; 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-8-amine, N-Boc-protected; Boc-8-amino-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 8-((tert-Butoxycarbonyl)amino)-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 1,4-Dioxino[2,3-b]pyridine-8-carbamic acid tert-butyl ester; BOC-DHDP
EINECS	Contact for details

Quality Control

Our tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.