Description

tert-Butyl (3-Iodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Carbamate is a high-value, multi-functional heterocyclic building block designed for advanced pharmaceutical and agrochemical research. Its complex molecular architecture, featuring iodine, trifluoromethyl, and a protected amine, makes it a critical intermediate for constructing novel bioactive compounds. This product is essential for medicinal chemists and process development scientists in the pharmaceutical and life sciences industries seeking to develop new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor for novel active ingredients in crop protection products, leveraging the bioactivity of the pyrrolopyridine core.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl (3-Iodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Carbamate
CAS No.	1346447-34-4
Molecular Formula	C13H11F3IN3O2
Molecular Weight	425.15 g/mol
Synonyms	4-((tert-Butoxycarbonyl)amino)-3-iodo-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; tert-Butyl N-[3-iodo-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]carbamate; 1H-Pyrrolo[2,3-b]pyridine-4-carboxamide, N-(1,1-dimethylethyl)-3-iodo-5-(trifluoromethyl)-; Boc-Protected 3-Iodo-5-Trifluoromethyl-7-Azaindole-4-Amine; 3-Iodo-5-(trifluoromethyl)-4-((tert-butoxycarbonyl)amino)-7-azaindole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of tert-Butyl (3-Iodo-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Carbamate is characterized and controlled using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency on specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.