Description

5-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine-6-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated and formylated structure, which provides multiple reactive sites for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used to develop novel fungicides and herbicides by acting as a core scaffold for bioactive molecules.
• Material Science: Serves as a building block for creating organic semiconductors and photoactive materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bioconjugates for biological studies.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Library Synthesis: A versatile starting material for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	5-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine-6-Carbaldehyde
CAS No.	1346447-32-2
Molecular Formula	C8H4ClIN2O
Molecular Weight	306.49 g/mol
Synonyms	5-Chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-6-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-6-carboxaldehyde, 5-chloro-3-iodo-; 5-Chloro-3-iodo-7-azaindole-6-carbaldehyde; 6-Formyl-5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine-6-carbaldehyde; 1346447-32-2
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.