Description

n-(3-(3-Hydroxypropyl)-5-(Trifluoromethyl)-Pyridin-2-Yl)Pivalamide is a high-value, multi-functional organic intermediate characterized by its pyridine core and trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique structural motifs into novel molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to its pyridine nitrogen and functional handles.
• Material Science Research: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	n-(3-(3-Hydroxypropyl)-5-(Trifluoromethyl)-Pyridin-2-Yl)Pivalamide
CAS No.	1346447-27-5
Molecular Formula	C14H19F3N2O2
Molecular Weight	304.31 g/mol
Synonyms	Pivalamide, N-[3-(3-hydroxypropyl)-5-(trifluoromethyl)-2-pyridinyl]-; 2-Pyridineacetamide, N-[3-(3-hydroxypropyl)-5-(trifluoromethyl)-2-pyridinyl]-2,2-dimethyl-; N-(3-(3-Hydroxypropyl)-5-(trifluoromethyl)pyridin-2-yl)-2,2-dimethylpropanamide; 1346447-27-5; UNII-9F6F8G4R4I
EINECS	Contact for details

Quality Control

Our n-(3-(3-Hydroxypropyl)-5-(Trifluoromethyl)-Pyridin-2-Yl)Pivalamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.