Description

5-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and developers seeking to introduce complex molecular architectures into their target molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Chemical Biology Probe: Acts as a versatile scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers due to its electron-rich fused ring system.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	5-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1346447-25-3
Molecular Formula	C₁₈H₁₁IN₂O₄S
Molecular Weight	478.26 g/mol
Synonyms	5-Iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-iodo-1-(phenylsulfonyl)-; 1346447-25-3; 5-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 1346447-25-3); Pyrrolopyridine-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 5-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.