Description

6-Chloro-n-Methoxy-n-Methyl-5-Pivalamidopicolinamide is a high-purity, advanced pharmaceutical intermediate with the CAS number 1346447-20-8. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in kinase inhibitor research.
• Agrochemical Research: Used in the development of advanced crop protection agents and herbicides.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry.
• Process Development: Employed in route scouting and optimization for scalable API manufacturing.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for client-specific projects.

Basic Information

Product Name	6-Chloro-n-Methoxy-n-Methyl-5-Pivalamidopicolinamide
CAS No.	1346447-20-8
Molecular Formula	C14H18ClN3O3
Molecular Weight	311.76 g/mol
Synonyms	6-Chloro-N-methoxy-N-methyl-5-(2,2-dimethylpropanamido)picolinamide; 5-Pivalamido-6-chloro-N-methoxy-N-methylpicolinamide; 6-Chloro-5-(pivalamido)-N-methoxy-N-methylpyridine-2-carboxamide; 1346447-20-8; Picolinamide, 6-chloro-N-methoxy-N-methyl-5-(2,2-dimethyl-1-oxopropoxy)-; 6-Chloro-N-methoxy-N-methyl-5-(pivalamido)picolinamide
EINECS	Contact for details

Quality Control

Our 6-Chloro-n-Methoxy-n-Methyl-5-Pivalamidopicolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.