Description

3-Amino-5-(3-Hydroxyprop-1-Yn-1-Yl)Picolinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining amino, cyano, and hydroxyl-alkyne functionalities. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex, targeted molecules. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or activity-based probes due to its reactive alkyne handle.
• Material Science: Potential monomer or cross-linker for specialty polymers with tailored properties.
• Academic & Contract Research: Employed in organic synthesis and methodology development within university and CRO laboratories.

Basic Information

Product Name	3-Amino-5-(3-Hydroxyprop-1-Yn-1-Yl)Picolinonitrile
CAS No.	1346447-12-8
Molecular Formula	C9H7N3O
Molecular Weight	173.17 g/mol
Synonyms	5-(3-Hydroxyprop-1-yn-1-yl)-3-aminopicolinonitrile; 3-Amino-5-(3-hydroxypropynyl)picolinonitrile; 2-Cyano-5-(3-hydroxy-1-propynyl)-3-aminopyridine; 3-Amino-5-(3-hydroxyprop-1-ynyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 3-amino-5-(3-hydroxy-1-propynyl)-; 1346447-12-8
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(3-Hydroxyprop-1-Yn-1-Yl)Picolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.