Description

(5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both halogen substituents and a hydroxymethyl group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated pyrrolopyridine scaffold.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive handle.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized heterocycles.

Basic Information

Product Name	(5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol
CAS No.	1346446-92-1
Molecular Formula	C8H6ClIN2O
Molecular Weight	308.50 g/mol
Synonyms	4-(Hydroxymethyl)-5-chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine-4-methanol; (5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridin-4-yl)methanol; 1H-Pyrrolo[2,3-b]pyridine-4-methanol, 5-chloro-6-iodo-; 5-Chloro-6-iodo-4-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of (5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.