Description

Methyl 6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylate is a high-value, heterocyclic organic compound featuring a fused pyranopyridine core structure with an iodine substituent. This molecule serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: The iodine atom provides a reactive site for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection and pest management.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	Methyl 6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylate
CAS No.	1346446-88-5
Molecular Formula	C10H10INO3
Molecular Weight	319.10 g/mol
Synonyms	Methyl 6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine-8-carboxylate; 6-Iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine-8-carboxylic acid methyl ester; 8-Methoxycarbonyl-6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine; 1346446-88-5; Methyl 6-iodo-2H,3H,4H-pyrano[3,2-b]pyridine-8-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.