Description

6-Bromo-5-Methylpyrazolo[1,5-A]Pyridine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrazolopyridine core.
• Material Science Precursor: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create tool compounds for target validation and biochemical pathway studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	6-Bromo-5-Methylpyrazolo[1,5-A]Pyridine
CAS No.	1345121-23-4
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	6-Bromo-5-methylpyrazolo[1,5-a]pyridine; 5-Methyl-6-bromopyrazolo[1,5-a]pyridine; Pyrazolo[1,5-a]pyridine, 6-bromo-5-methyl-; 1345121-23-4; 6-Bromo-5-methyl-1H-pyrazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methylpyrazolo[1,5-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications from early-stage research to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.