Description

3-Fluoro-2-Morpholinopyridin-4-Ol is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of fluorine and morpholine substituents on the pyridine scaffold, enabling precise modulation of molecular properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where it serves as a key intermediate for creating compounds with enhanced bioavailability and target specificity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, receptor modulators, and other small-molecule drug candidates targeting a range of therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved metabolic stability and efficacy.
• Chemical Biology Probe Synthesis: Employed to create labeled or tagged molecules for studying biological pathways and protein-ligand interactions.
• Material Science Research: Serves as a building block for advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this specialized scaffold.

Basic Information

Product Name	3-Fluoro-2-Morpholinopyridin-4-Ol
CAS No.	1344046-08-7
Molecular Formula	C9H11FN2O2
Molecular Weight	198.20 g/mol
Synonyms	4-Pyridinol, 3-fluoro-2-(4-morpholinyl)-; 3-Fluoro-2-morpholin-4-ylpyridin-4-ol; 2-Morpholino-3-fluoropyridin-4-ol; 3-Fluoro-2-(morpholin-4-yl)pyridin-4-ol; 4-Hydroxy-3-fluoro-2-morpholinopyridine; 1344046-08-7; 3-Fluoro-2-morpholinopyridin-4-ol
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Morpholinopyridin-4-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.