Description

6-Amino-[1,2,4]triazolo[4,3-a]pyridin-3-ol is a high-value, nitrogen-rich heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused triazolo-pyridine structure makes it a versatile intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-infective compounds.
• Agrochemical Research: Used in developing new classes of herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and corrosion inhibitors.
• Chemical Synthesis: A versatile synthon for constructing complex polyheterocyclic systems in medicinal and combinatorial chemistry.
• Bioconjugation & Probe Development: Utilized in designing fluorescent probes, biochemical tags, and linker molecules for diagnostic applications.

Basic Information

Product Name	6-Amino-[1,2,4]triazolo[4,3-a]pyridin-3-ol
CAS No.	1343323-60-3
Molecular Formula	C6H5N5O
Molecular Weight	163.14 g/mol
Synonyms	6-Amino-3-hydroxy-[1,2,4]triazolo[4,3-a]pyridine; 3-Hydroxy-6-amino-[1,2,4]triazolo[4,3-a]pyridine; 6-Amino-1,2,4-triazolo[4,3-a]pyridin-3-ol; [1,2,4]Triazolo[4,3-a]pyridin-3-ol, 6-amino-; ATAP-OH; 6-ATPO
EINECS	Contact for details

Quality Control

Our 6-Amino-[1,2,4]triazolo[4,3-a]pyridin-3-ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.