Description

1-(Pyrazin-2-Yl)Azetidin-3-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Synthesis: Employed as a building block for developing new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up under cGMP conditions for clinical trial material.
• Library Synthesis: Ideal for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	1-(Pyrazin-2-Yl)Azetidin-3-Ol
CAS No.	1342906-03-9
Molecular Formula	C7H9N3O
Molecular Weight	151.17 g/mol
Synonyms	3-Hydroxy-1-(pyrazin-2-yl)azetidine; 1-(2-Pyrazinyl)-3-azetidinol; Azetidin-3-ol, 1-(2-pyrazinyl)-; 1-Pyrazin-2-ylazetidin-3-ol; 3-Azetidinol, 1-(2-pyrazinyl)-; 1-(Pyrazin-2-yl)azetidin-3-ol; 1342906-03-9 (CAS)
EINECS	Contact for details

Quality Control

Our 1-(Pyrazin-2-Yl)Azetidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) with complete chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.