Description

1-Pyrazin-2-Yl-Azetidine-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique azetidine-pyrazine scaffold makes it a critical intermediate for constructing novel molecular architectures with targeted biological activity. This compound is primarily utilized by pharmaceutical R&D and agrochemical organizations engaged in the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for creating new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Used in the synthesis of molecular probes to study enzyme function and protein-protein interactions.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, enabling new synthetic transformations.
• Peptidomimetics & Constrained Peptide Design: The azetidine ring provides conformational restraint, making it valuable for designing bioactive peptide analogs.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specific electronic or photophysical properties.

Basic Information

Product Name	1-Pyrazin-2-Yl-Azetidine-3-Carboxylic Acid
CAS No.	1342386-90-6
Molecular Formula	C8H9N3O2
Molecular Weight	179.18 g/mol
Synonyms	Azetidine-3-carboxylic acid, 1-(2-pyrazinyl)-; 1-(Pyrazin-2-yl)azetidine-3-carboxylic acid; 3-Carboxy-1-(2-pyrazinyl)azetidine; 1-(2-Pyrazinyl)azetidine-3-carboxylic acid; Azetidine-3-carboxylic acid, 1-pyrazin-2-yl-; 1342386-90-6; 1-Pyrazin-2-ylazetidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Pyrazin-2-Yl-Azetidine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.