Description

3-Amino-1-Cyclopropyl-1,2-Dihydropyrazin-2-One is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug molecules, particularly in oncology and anti-infective therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural unit in the multi-step synthesis of complex target APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Preclinical Drug Development: Essential for producing gram to kilogram quantities of candidate compounds for pharmacological and toxicological evaluation.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of proprietary compounds under cGMP guidelines.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	3-Amino-1-Cyclopropyl-1,2-Dihydropyrazin-2-One
CAS No.	1342156-93-7
Molecular Formula	C7H10N4O
Molecular Weight	166.18 g/mol
Synonyms	3-Amino-1-cyclopropyl-1,2-dihydropyrazin-2-one; 1-Cyclopropyl-3-amino-1,2-dihydropyrazin-2-one; 2(1H)-Pyrazinone, 3-amino-1-cyclopropyl-1,2-dihydro-; 3-Amino-1-cyclopropyl-1,2-dihydro-2-pyrazinone; 1-Cyclopropyl-3-amino-1,2-dihydro-2-pyrazinone; 3-Amino-1-cyclopropylpyrazin-2(1H)-one; ACPO (common abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Amino-1-Cyclopropyl-1,2-Dihydropyrazin-2-One is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We support development and commercial projects with consistent quality that meets the stringent requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.