Description

2-(Oxolan-3-Yloxy)Pyridin-4-Amine is a heterocyclic organic compound featuring a pyridine core linked to a tetrahydrofuran (oxolane) moiety via an ether bridge. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The compound's amine group provides a key handle for further chemical modifications, enabling the creation of diverse molecular libraries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry to create novel compounds for biological evaluation.
• Agrochemical Research: Serves as a precursor in the synthesis of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold.
• Ligand Synthesis: Potential use in the development of novel ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Can be functionalized to create tools for studying biological processes and target identification.

Basic Information

Product Name	2-(Oxolan-3-Yloxy)Pyridin-4-Amine
CAS No.	1339933-64-0
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	4-Amino-2-(tetrahydrofuran-3-yloxy)pyridine; 2-(Tetrahydro-3-furanyloxy)-4-pyridinamine; 4-Pyridinamine, 2-[(tetrahydro-3-furanyl)oxy]-; 2-(Oxolan-3-yloxy)pyridin-4-amine; 2-(3-Furanyloxy)-4-pyridinamine (pre-hydrogenation); 4-Amino-2-(3-furyloxy)pyridine (precursor); 2-(Tetrahydrofuran-3-yloxy)-4-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-(Oxolan-3-Yloxy)Pyridin-4-Amine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment. Our quality commitment supports your regulatory compliance needs for preclinical and early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.