Description

tert-Butyl 2-Aminopyridine-4-Carboxylate is a high-value, protected aminopyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in facilitating efficient and selective synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and heterocyclic medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, and other functional organic compounds.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	tert-Butyl 2-Aminopyridine-4-Carboxylate
CAS No.	1338990-46-7
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	2-Amino-4-(tert-butoxycarbonyl)pyridine; 4-Carboxy-2-aminopyridine tert-butyl ester; tert-Butyl 2-aminoisonicotinate; 2-Aminopyridine-4-carboxylic acid tert-butyl ester; 2-Aminoisonicotinic acid tert-butyl ester; 4-(tert-Butoxycarbonyl)-2-aminopyridine; TBOC-2-Amino-4-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Aminopyridine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.