Description

2-(4-Fluoro)-Phenylpyrazolo[1,5-A]Pyrazin-4(5H)-One is a high-purity fluorinated heterocyclic compound, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique pyrazolopyrazinone scaffold, which is integral to the synthesis of novel bioactive molecules targeting various therapeutic areas. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry and process optimization for new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its fused heterocyclic core.
• Agrochemical Development: Serves as a precursor in the research of new herbicides, fungicides, or insecticides with enhanced activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-up: Employed in route scouting and pilot-scale synthesis for the commercial production of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-(4-Fluoro)-Phenylpyrazolo[1,5-A]Pyrazin-4(5H)-One
CAS No.	1338692-17-3
Molecular Formula	C12H8FN3O
Molecular Weight	229.21 g/mol
Synonyms	2-(4-Fluorophenyl)pyrazolo[1,5-a]pyrazin-4(5H)-one; 2-(4-Fluorophenyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-4-one; 1338692-17-3; 2-(p-Fluorophenyl)pyrazolo[1,5-a]pyrazin-4(5H)-one; Pyrazolo[1,5-a]pyrazin-4(5H)-one, 2-(4-fluorophenyl)-; SCHEMBL21829027; AKOS040759232; FT-0775787
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro)-Phenylpyrazolo[1,5-A]Pyrazin-4(5H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent chemical identity, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and spectral data (NMR, HPLC, MS) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.