Description

1-Boc-4-Hydrazinocarbonylmethyl Piperazine is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual functional groups, which enable precise chemical modifications and the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce hydrazide and protected amine functionalities into peptide backbones for creating stable, bioavailable analogs.
• Linker Molecule in Bioconjugation: Facilitates the attachment of drugs, dyes, or other payloads to antibodies, proteins, or nanoparticles in ADC (Antibody-Drug Conjugate) and diagnostic probe development.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of functional polymers and smart materials.
• Chemical Biology Probes: Useful for designing activity-based probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	1-Boc-4-Hydrazinocarbonylmethyl Piperazine
CAS No.	1338673-52-1
Molecular Formula	C11H21N3O3
Molecular Weight	243.31 g/mol
Synonyms	1-Boc-4-(2-Hydrazinyl-2-oxoethyl)piperazine; tert-Butyl 4-(2-hydrazinyl-2-oxoethyl)piperazine-1-carboxylate; 4-(2-Hydrazinyl-2-oxoethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(hydrazinecarbonylmethyl)piperazine; N-Boc-4-(hydrazinocarbonylmethyl)piperazine; Piperazine-1-carboxylic acid, 4-(2-hydrazinyl-2-oxoethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Hydrazinocarbonylmethyl Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications in cGMP and ISO-certified environments, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping it under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.