Description

3-tert-Butyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-B]Pyridine CAS NO 1338247-69-0 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. This compound is essential for medicinal chemistry teams and process development scientists in pharmaceutical R&D and fine chemical manufacturing who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Serves as a core structure for synthesizing potential therapeutics for neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of investigational small-molecule inhibitors for cancer treatment.
• Chemical Biology: Utilized as a probe or tool compound for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Supplied in development and commercial quantities for route scouting and GMP manufacturing campaigns.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and manufacturing services.

Basic Information

Product Name	3-tert-Butyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1338247-69-0
Molecular Formula	C10H17N3
Molecular Weight	179.26 g/mol
Synonyms	3-tert-Butyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 4,5,6,7-tetrahydro-3-(1,1-dimethylethyl)-; 3-(tert-Butyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine; 3-tert-Butyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine; 3-tert-butyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine; 3-tert-Butyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-b]pyridine; Pyrazolopyridine intermediate 1338247-69-0
EINECS	Contact for details

Quality Control

Our 3-tert-Butyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with data from advanced techniques like HPLC, GC, NMR, and MS. Our quality commitment aligns with the standards expected by the pharmaceutical and fine chemical industries for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.