Description

(3R)-3-(4-Bromophenyl)Piperidine CAS NO 1336754-69-8 is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its defined stereochemistry and functionalized aromatic ring, which are essential for constructing complex molecules with specific biological activity. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) targeted drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(3R)-3-(4-Bromophenyl)Piperidine
CAS No.	1336754-69-8
Molecular Formula	C11H14BrN
Molecular Weight	240.14 g/mol
Synonyms	(R)-3-(4-Bromophenyl)piperidine; (3R)-3-(4-Bromophenyl)piperidine; 3-(4-Bromophenyl)piperidine, (3R)-; 4-Bromo-α-piperidinobenzyl alcohol (related); (R)-3-(p-Bromophenyl)piperidine; (3R)-3-(p-Bromophenyl)piperidine; 1-(4-Bromophenyl)-3-piperidinol (tautomer); BRN 8230423
EINECS	Contact for details

Quality Control

Our (3R)-3-(4-Bromophenyl)Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) verification by chiral HPLC, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.